An escaped con, on the run from the law, moves into a married couple's house and takes over their lives.

Mark Kaminsky is kicked out of the FBI for his rough treatment of a suspect. He winds up as the sheriff of a small town in North Carolina. FBI Chief Harry Shannon, whose son has been killed by a mobster named Patrovina, enlists Kaminsky in a personal vendetta with a promise of reinstatement into the FBI if Patrovina is taken down. To accomplish this, he must go undercover and join Patrovina's gang.

In Black Death era Tuscany, as in the Decameron, ten young Florentines take refuge from the plague. But instead of telling stories, they have lusty adventures, bawdy exchanges, romance, swordplay, randy nuns, Saracen pirates, and a sexy cow.

After a particularly grueling case hunting a serial killer known as the Minnesota Shrike, Will Graham threatens to walk away. Jack Crawford, the head of the FBI's Behavioral Science Unit, desperately needs Will on his team to break the tough cases, so he enlists Dr. Hannibal Lecter, to ensure Will's mental well-being. Unbeknownst to Will, Hannibal also has a particular insight into these horrible crimes and the psychopaths who commit them. As Will hunts down brutal killers, he is unknowingly sitting across from the most gifted killer of them all.