In a godforsaken bar in the middle of nowhere, an all-girl band – Ms. 45 – rips the stage apart with their punk spirit. But their performance impresses an enthusiastic fan who lures the girls into a trap, sedates them, and starts…customizing them. Slowly they begin to gain consciousness and, in total shock, realize their arms have all been replaced with axes and chainsaws to fight gladiator-style in a junkyard arena owned by a sadistic "emperor," forcing them into the battle of their lives with one prize in mind – their freedom.

带着愤怒和决心，失声的卡尔玛（谢拉·贝尔夏 Shera Bechard 饰）走出了国门，她此行的目的只有一个，那就是找到早年被人贩拐卖的姐姐安娜（Patricia Stasiak饰）。凭借着手上收集的线索，卡尔玛迅速找到了人口贩卖团伙中的两名成员，可是在痛下杀手之后，她也成为了黑白两道追捕的对象。
一次意外让卡尔玛落入了人贩的手中，虽然遭受了被侮辱的悲惨命运，但这一事件让卡尔玛顺利的打入了敌人的内部。卡尔玛杀死了暴徒，释放了被他们囚禁的女人们，通过这些人之口，卡尔玛得知姐姐早已不在人世。但事实却并非如此，当卡尔玛带着满身鲜血站在人贩头目的面前之时，安娜的突然出现将她的一切自信和努力全然推翻。