Set in the mythical world of Rhymeland, Gordon Goose returns home to discover that his mom has mysteriously vanished. Now the characters of Rhymeland are in danger of disappearing unless Mother Goose returns.

Widowed pediatrician Harry Weston is a miracle worker when it comes to dealing with his young patients, but he's more challenged by the other people surrounding him: daughters Barbara and Carol; his wisecracking office assistant, nurse LaVerne Todd; and obnoxious neighborhood mooch Charley Dietz. Thank goodness he always finds a friendly shoulder (and a warm, wet tongue) in Dreyfuss, his enormous dog.