In the year 2024, the ozone layer is believed to have been destroyed, and it's up to MacLeod and Ramirez to set things right. Opposition comes from both the planet Ziest (MacLeod and Ramirez's homeworld) and a corporation profiting from the supposed lack of ozone. Also, flashbacks show the story behind MacLeod and Ramirez's exile from Ziest.

Starts off in the 15th century, with Connor McLeod training with another immortal swordsman, the Japanese sorcerer Nakano. When an evil immortal named Kane kills the old wizard, the resulting battle leaves him buried in an underground cave. When Kane resurfaces in the 20th century to create havoc, it's up to McLeod to stop him.