Not long after twin brothers Ryuichi and Ryuji were born, they were abandoned by their own parents. They were then adopted by the Yoshie couple, who ran a small shipping company. Sometime later, the Yoshies gave birth to their daughter Misa. Ryuichi and Ryuji enjoyed pleasant days with their adopted parents and younger sister Misa. When Ryuichi and Ryuji were 15-years-old, their parents experienced extremely dark days because of Genpei Kirishima, who ran a competing shipping company.

本剧改编自同名漫画，讲述了在某次事故中脑损伤，患有严重后遗症的脑外科医生川内雅，不仅过去两年的记忆完全消失，新的记忆也不能停留一天以上。因此，小雅变得只能做护士的辅助工作，但是在她面前，出现了怪人脑外科医生三瓶友治。通过他不读空气、随心所欲但又带来帮助和引导的言行，小雅在作为患者的同时，再次踏上了作为医生的道路。不久，小雅那消失的两年记忆中所隐藏的谜团被揭开...