After a doctor kills his mistress and himself while researching the mysterious previous owner of his Boston home, his colleague, Dr. Norman Boyle, takes over his studies and moves his family into the Boston mansion. Soon after, Boyle's young son Bob becomes plagued by visions of a young girl, who warns him of the danger within the house.

Three girls discover that two men are willing to do anything to impress Mother and what impresses Mother is watching her sons commit acts of rape and murder. Now these women are prisoners and lowered to pawns in the game of checkers between two dim wits and their Maniac Mommy and the question becomes, can any of them escape, alive?