In Ancient Polynesia, when a terrible curse incurred by Maui reaches an impetuous Chieftain's daughter's island, she answers the Ocean's call to seek out the demigod to set things right.

As Stitch, a runaway genetic experiment from a faraway planet, wreaks havoc on the Hawaiian Islands, he becomes the mischievous adopted alien "puppy" of an independent little girl named Lilo and learns about loyalty, friendship, and ʻohana, the Hawaiian tradition of family.