After discovering her father put their house up for his bail bond and then disappeared, 17-year-old Ree Dolly must confront the local criminal underworld and the harsh Ozark wilderness in order to to track down her father and save her family.

After her husband deserts her, working-class mother Ray Eddy is in great need of money to find a home. Lured by the possibility of easy cash, she joins Lila, a widowed Mohawk who earns a living by smuggling immigrants from Canada to the U.S. across the St. Lawrence.