Doctor Strange, with the help of mystical allies both old and new, traverses the mind-bending and dangerous alternate realities of the Multiverse to confront a mysterious new adversary.

Peter Parker is unmasked and no longer able to separate his normal life from the high-stakes of being a super-hero. When he asks for help from Doctor Strange the stakes become even more dangerous, forcing him to discover what it truly means to be Spider-Man.

Shang-Chi must confront the past he thought he left behind when he is drawn into the web of the mysterious Ten Rings organization.