Thirty years after the events of the first film, a new blade runner, LAPD Officer K, unearths a long-buried secret that has the potential to plunge what's left of society into chaos. K's discovery leads him on a quest to find Rick Deckard, a former LAPD blade runner who has been missing for 30 years.

When an IMF mission ends badly, the world is faced with dire consequences. As Ethan Hunt takes it upon himself to fulfill his original briefing, the CIA begin to question his loyalty and his motives. The IMF team find themselves in a race against time, hunted by assassins while trying to prevent a global catastrophe.

In 1926, Newt Scamander arrives at the Magical Congress of the United States of America with a magically expanded briefcase, which houses a number of dangerous creatures and their habitats. When the creatures escape from the briefcase, it sends the American wizarding authorities after Newt, and threatens to strain even further the state of magical and non-magical relations.