Sabrina Spellman, a perfectly normal 16-year-old, is informed by her aunts, Hilda and Zelda, that she (and they, and her whole family on her father's side) are witches. She lives with them in Massachusetts while preparing to receive her witch's license. Along the way, she gets into many scrapes while figuring out how certain spells work. She also has to keep the secret from her boyfriend, Harvey, friends Jenny and later Valerie, stuck-up nemesis Libby, and her ever-suspicious vice-principal, Mr. Kraft.

当一个16岁的高中生发现她是个女巫时，她的两个阿姨就指导她如何控制新发现的魔法力量。