因女儿夭亡，伤心的杰克（Reynaldo Rosales 饰）和斯蒂芬妮（Heidi Dippold 饰）夫妇决定前往另一个城市生活。当他们行驶在阿拉巴马的荒漠中时，突然遭遇离奇车祸，在没有其他车辆经过和手机信号覆盖的情况下，夫妇俩只能弃车步行前进。
夜幕降临，大雨滂沱，狼狈的夫妇俩总算找到一间小屋借以栖身。小屋中住着怪异的三口之家，同时还有另一对因车祸来此落脚的夫妇。是夜，诡异恐怖之事接连发生，原本是避难的场所，一夜之间变成了生死抉择的行刑地……

Leslie Easterbrook plays the lead role of 'Mother Maggie', a disturbed mother of four who delivers an unimaginable level of abuse to her children while defending her actions with her own twisted interpretations of the Bible. Three daughters live in constant fear of being beaten and abused by their mentally disturbed mother. Escaping the wrath of their mother seems impossible and proves to be deadly. Based on a true story, The Afflicted takes you inside the lives of those who live in constant fear with no escape.

《千尸屋2》是2003年卖座恐怖片《千尸屋》续集，2005年7月22日上映。由罗布·祖姆比执导，西德·海格、比尔·默瑟利等主演。电影讲述，嗜血成性、精神变态的法尔弗莱一家以杀人为乐，然而，他们也正在成为别人掌中的猎物。

Several college students are brutally murdered in a small college town an the killer is still on the loose...