Since the anesthesiologist Lu Yan “runs into” her dead college friend Deng Man during a night shift, strange things around her occur successively. As the investigation proceeds, the detective Jiang Chengyi, Lu Yan’s ex-boyfriend from many years ago, is embroiled in it, and the long-hidden truth of eight years is gradually revealed.

After losing her parents in a tragic accident, Zhuo Yifeng suppresses her past through selective amnesia and takes on a new identity as Su Nianfeng. Raised by her parents' friend alongside his son, Su Muyun, she struggles with an uneasy sibling-like relationship. As she navigates high school, Su Nianfeng finds inspiration in her close friend Yue Diyin, whose warmth and resilience motivate her to pursue a career in medicine despite his battle with a mysterious illness.

召族圣女姜玉葵（戚砚笛 饰），自幼囚笼求生，惊闻姐姐惨死，携司命之力复仇。九千岁丰烨（肖凯中 饰）将她掳至身边，二人从试探到相爱，联手对抗暴君毒后。不料姐姐未死，竟是幕后黑手，多年筹谋只为夺权。双生迷局揭晓，爱恨终抵宿命，共赴照殿花开……