荷拔韦斯医生和他的助手丹凯恩再次尝试使死人复活，他们找来密斯科汤尼克医学院大屠杀的死人肢体，这次要把丹前任女友的心脏，放进“组装完美”的身体里，试图重造他的女友，但却发生意想不到的结果，而希尔医生只剩下一只头颅回来复仇。
这第二部比第一部更加变本加厉的离奇夸张：接在小狗身上的人手、眼球和手指组合的恶心怪物以及插上两只蝙蝠翅膀而会飞的人头等都让观看影片的观众张大了嘴，尤其影片最后的高潮部分“拼凑美女”更是让我们沉醉于无限的惊恐与恶心当中。

After a small earthquake in a small and quiet town, local citizens start to have a bizarre, violent and self-destructive behavior...

The multi-media misadventures of a mismatched pair of buddies, "Downer" and Nash, one in search of his long lost father, the other in search of the ultimate sexual video game competition. What their odyssey leads them to are some far-out encounters with a demented midget, a transsexual nun, a drunken lunatic, a rabbi landlady and a sex starved beach bunny.