A young Japanese actress remembers her war childhood in Korea. Her father goes to fight, her baby sister Miko dies of typhoid, her beloved Korean maid Ohana is fired due to a mistake which could cost Chiko her life... By and by Chiko realizes that the country is being ruled by the Japanese and the Koreans are persecuted. When the war ends, the Koreans chase the Japanese rule and the roles change. Now Chiko's family is unwanted. But then the Russians come and this is the end. They have to burn all the pictures to avoid all suspicions... even Miko's picture. But when the Russians come to their house, they decide to flee over the 38th Parallel towards freedom. A group of men, women, children struggles along the mountains, led by the light of the Northern Star. Along the way they meet a Korean man, who is willing to help them to escape the Russian soldiers although his family was killed by the Japanese.

After a meteor hits Earth, traitor forces have (for all intents and purposes) taken over, and the people are suffering. In the chaos, a boy named Tetsuro Daiba, who had lost his parents in the meteor hit, is paid a visit by Mello, a mysterious woman appearing in a bright light. When Daiba comes to, he finds itself in a spaceship infirmary under observation. Stealing a fighter that he didn't know how to pilot (until he tried it), he breaks out, flying like a total pro.

According to an ancient Japanese legend, mermaid flesh may grant immortality if eaten. However, there is a much greater chance that consumption will lead to death or transformation into a damned creature known as a Lost Soul (or Deformed Ones in the English dub). Mermaid Saga tells the tale of Yuta, an immortal who has been alive for five hundred years, who is wandering across Japan searching for a cure and meeting others whose lives have also been ruined by mermaid flesh in the process.