The Bowery Boys open a nightclub after Sach has his tonsils out and wakes up with a singing voice.

While Louie is on vacation, the boys turn The Sweet Shop into a male escort service, and soon find a group of beautiful girls as their first clients.

While working in a laundromat, the boys find a baby hidden among the linen. They soon find out that the baby, who is the heir to a fortune, has been abandoned by his mother so that her two evil aunts can't cheat her and the baby out of the inheritance. The boys determine to help the woman claim her baby's rightful inheritance from her aunts, who have hired gangsters to find and eliminate the girl, the baby and anyone who helps them.

Sach is given a post-hypnotic suggestion that turns him into a championship prizefighter.

Muggs and Glimpy, two East Side Kids in the army, return to their neighborhood, supposedly on furlough; actually, Muggs has been honorably discharged with a physical defect, but he tells no one of this. Danny, another East Side kid, is in jail because a large amount of medical supplies have been stolen from the warehouse where he works. Muggs see Spider, a new member of the gang, flashing a large amount of money around, and Muggs shrewdly turns toughie, boasting that he has a dishonorable discharge because of thievery. This leads Spider to confide in Muggs that he is the one who has been aiding in the theft of supplies from the warehouse, and he gets paid for the loot by Larry, operator of a nightclub where Muggs' sister, Milly, is an entertainer. Fingers, a henchman for Larry, kills Spider when he learns that Muggs has been let in on the operation. The police then suspect Muggs of killing Spider.

A young man just released from a reformatory moves to a new neighborhood with his sister, intending to start a new life. However, he gets mixed up with the local mob boss and corrupt politicians and soon finds himself being framed for an arson and murder he didn't commit.

Rejected by the Army, Marines, and Navy for being too young, the punks help the war effort by throwing fruit at a shop they believe is owned by a Japanese American. Confronted by him wielding a short sword, the gang decides to come back at night but find him dead.

In ridding the area of muggers, the East Side Boys acquire a wealthy benefactor whose privileged son, unbeknownst to him, has fallen in with thugs.

The East Side Kids find a young girl in the apartment of a man who has just been murdered. Believing her to be innocent, they hide her in their clubhouse while they try to find the real killer. The killer, however, used a baseball bat as his murder weapon, and the bat has the fingerprints of one of the gang on it.

Slip, Sach and the rest of the Bowery Boys enter a haunted house, where they engage in slapstick with a gorilla, a robot and a vampire

The Bowery Boys--Slip, Sach, Bobby, Whitey & Chuck--start their own exterminating service, and get a job which takes them to a spooky old abandoned mansion in the middle of the night. Meeting up with pal Gabe and his new French bride, the boys are tormented by mad scientists who try to convince them the place is haunted and then kidnap Sach in order to place his brain inside a gorilla.

In the slums, teenager Frankie Warren hangs out with a rowdy gang who one day knock him out in a fight. In court, the boys refuse to reveal who struck the knockout blow, and all are subsequently sentenced to a reformatory, cruelly run by two corrupt guards. New deputy commissioner Mark Braden arrives determined to change things, but despite the help of Frankie's sister, Mark's reform plans -- and Frankie's future -- may be sabotaged from within.

The living Volkswagen Beetle helps an old lady protect her home from a corrupt developer.