山姆是玩世不恭的花花公子，他的麻吉安德魯則是一名婦科醫生。某次派對後，山姆一覺醒來發現自己變成女人了，於是自稱山姆的表妹珊曼莎，接續山姆的工作，這才了解身為女性多不容易，主管對他毛手毛腳，更可怕的是叫作生理期的東西。最要命的是只要想起安德魯，他居然起了生理反應。這是上天的玩笑還是懲罰？

影片根据哈罗德罗宾斯的小说改编，分为两部四个小时。故事描述一位早期电影制作人(Mark Harmon扮演), 20世纪初带着梦想来到好莱坞，将加利福尼亚这块沉睡的土地建设成世界娱乐中心。

伊尔玛是一位百万富翁的妻子，一天到晚只知道去商场购物。丈夫沃尔特退休后，她以为丈夫要谋害她，于是决定逃走。她逃到最好的朋友洛雷塔家里，遇到前来偷窃的特里萨，不明就里的伊尔玛跟着她来到她的住处。
特里萨和她的男友丹尼认为伊尔玛是一座金山，但在如何对待她的问题上却出现了分歧……

Puppy mayhem turns the lives of newlywed Chihuahua parents Papi and Chloe upside down when their rambunctious, mischievous puppies present one challenge after another. But when their human owners end up in trouble, the tiny pups will stop at nothing to save them - because in good times and hard times, the family always sticks together. So Papi, Chloe and the puppies embark on a heroic adventure, proving once again that big heroes come in small packages.

A popular anchorwoman, Jaime Douglas is stalked by an obsessed fan with a camera who wants more than just her picture.

Siren Phillips has lived her life thinking she's an ordinary girl, in an ordinary town. On the eve of her twelfth birthday, however, she learns that she is far from ordinary. Destined to turn into a Mermaid at the age of twelve, Siren must struggle with her new reality, saying good-bye to her mother and friends, while she transitions into the water. To make matters worse, a group of hunters are trying to catch her. She soon becomes friends with Adam Wilts, a new boy at school, who she turns to for help. He agrees to help her, but finds himself caught in the middle, when it's his own father who is after Siren. When Siren's mother is taken, the town must rally behind her, and help her make a peaceful transition into the water, before the hunters can find out where she is.

This intimate drama follows Rebecca, a woman who has kept her sexuality a secret from her friends but chooses to reveal it to a stranger. While Rebecca's revelations may not yield the results she expects, a perfect ending is still in reach.

The eccentric and childish Pee-wee Herman embarks on a big adventure when his beloved bicycle is stolen. Armed with information from a fortune-teller and a relentless obsession with his prized possession, Pee-wee encounters a host of odd characters and bizarre situations as he treks across the country to recover his bike.

利兹（安娜·亚历山大 Ana Alexander 饰）是一位精明强干的女警察，她杀伐决断的作风让警队里的男同事们都对她另眼相看，这也难怪，谁叫她在洛杉矶呢，在这里，不是你将敌人赶尽杀绝，就是被敌人逼得走投无路。
迈克尔（乔纳森·蔡斯 Jonathan Chase 饰）是一名前途无量的律师，工作中的他处处小心谨慎，仿佛走在刀锋边缘。细腻认真的个性让迈克尔十分擅长他的这份工作，与此同时，他和上司的女儿亦即将携手步入婚姻的殿堂。一场意外让利兹和迈克尔相遇了，两人之间碰撞出的欲望的火花让他们两人都感到震惊。当他们的关系如同野火燎原般的一发不可收拾时，他们要面对的是人生中种种关乎于道德的选择。

即将三十而立的马修（休斯顿·怀宁斯 Houston Rhines 饰），工作上总被骄横的老板呼喝，跟长期男友的感情也步入七年之痒。被工作和生活拖垮的他孤注一掷的求助网络。意外的是网络回应他了！一款叫“网路爱神”（eCupid）的应用软件保证为他配对完美的爱人。突然马修的生活变得仙乐飘飘，各类帅哥络绎不绝的找上门来，且个个符合他的性幻想。然而随着eCupid开始频繁干涉他的生活，马修隐约觉得，也许更应该听从自己内心，决定谁是生命中最爱的人......
软件可以通过研究人的网络足迹而配对真爱吗？假如有天程序开始干预你的现实行为，你会按照它说的做吗？“网路爱神”讲的就是一个近乎荒诞的故事。你会发现人与人的交友方式可以改变，但感情最终还得走心。