Kaliyoonjal movie portrays a brother to a disturbed sister. The sister, played by Shalini, is mentally disturbed if any thing goes against her will. She is possessive of her brother and creates a havoc when she gets angry. Enter Shobhana who marries Mammootty and Dileep, who plays Shobhana's brother and marries Shalini, and problems start up in the family.

Ramankutty, a teacher with good reputation, agrees to marry his uncle's daughter. His respect goes for a toss when he changes his mind and shows interest in another cousin.