故事发生在一个叫圣城的地方．一处建筑工地唤醒了成群响尾蛇．原来20年前．一辆运蛇车在此发生车祸．产生这种巨毒变异蛇．小镇人接二连三被这种蛇咬死．新来的消防局长维克决定保护镇里人．却处处遇阻．直到镇长的儿子也差点命丧蛇口……

An accountant sent to produce an evaluation of a tornado research project, and the scientist running the project pursue tornadoes and each other.